Is it possible to have two column layouts?

Update: We will support multiple columns on the upcoming MailPoet 3.

Our visual editor supports single column layout only  because:

1. Multiple columns look bad on mobile phones. In 2012, more than half of all opened emails were on cell phones, according to Return Path.
2. Email designs are already narrow because email clients offer limited real estate
3. Many email clients already have columns left and right of the email body, which clutters the view
4. We prioritized ease of use because most of our users aren't designers

You can create a two or even three column layout if you're are familiar with HTML for email. Read more here.